
The Zelrix acute-migraine patch introduced by Conshohocken-based NuPathe. Will it fight upstream to market?
Updated 9/18/09 @ 2:42 p.m. Name in title
When Jane Hollingsworth takes a pill to help fight a headache, she might get nauseous or sicker still.
More than half of American adults suffer similarly, she says, which is a bear of a nuisance for anyone with an acute migraine and a problem with the most common medicinal cure. Still many just put up with the pain.
Because it’s affecting millions of people who just might happily pay for a solution, there is admitted industry buzz swarming NuPathe, the Conshohocken-based specialty pharmaceutical company that says it could help everyone with a pain in their head who doesn’t want a pill to swallow. After a scheduled new drug application is filed next year, you just might know someone who uses Zelrix, a NuPathe-manufactured patch that secretes migraine-fighting medication into the bloodstream.

Jane Hollingsworth
“There is no patch for migraines now. There has never been,” says Hollingsworth, 50, the 25-employee company’s CEO who helped launch it in 2005. “It’s very difficult to get drugs through the skin quickly, which is important for migraines especially.”
Difficult for everybody else, she must mean. Because, as the company’s comprehensive phase-III trial data summary presentation suggested at last week’s 14th Congress of the International Headache Society held at the Convention Center, things for NuPathe are going, as Hollingsworth says, “exceedingly well.”
After the jump, the Ardmore native tells us how technology makes Zelrix work, why biomedical entrepreneurship in Philadelphia lags behind smaller hubs like Boston, why she has to cheer for the Flyers and more.
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